关键信息
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基因名
RAB6B
- 应用
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别名
RAB6B;Ras-related Protein Rab-6B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NRW1
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表达区间
1-208aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MSAGGDFGNP LRKFKLVFLG EQSVGKTSLI TRFMYDSFDN TYQATIGIDF LSKTMYLEDR TVRLQLWDTA GQERFRSLIP SYIRDSTVAV VVYDITNLNS FQQTSKWIDD VRTERGSDVI IMLVGNKTDL ADKRQITIEE GEQRAKELSV MFIETSAKTG YNVKQLFRRV ASALPGMENV QEKSKEGMID IKLDKPQEPP ASEGGCSC
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分子量
26 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
RAB6B is a member of the RAB family of small GTPases, which are crucial regulators of intracellular vesicle transport and membrane trafficking. It has garnered significant attention in recent years due to its potential roles in various cellular processes, including exocytosis, endocytosis, and Golgi apparatus function. Studies have indicated that RAB6B is involved in multiple cellular pathways, affecting processes such as cell signaling, cytoskeletal dynamics, and organelle communication. Given its relevance to critical cellular functions and the implications for numerous diseases, including cancer and neurodegenerative disorders, researchers have focused on producing recombinant RAB6B proteins. The generation of these proteins enables detailed biochemical and biophysical characterization, providing insight into its role in cellular mechanisms. Furthermore, understanding RAB6B's function could yield valuable information for developing therapeutic strategies targeting abnormal vesicle trafficking pathways associated with various pathologies. Overall, the study of RAB6B recombinant proteins is pivotal for elucidating the molecular underpinnings of cellular transport mechanisms and their impact on health and disease.
