| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | FAM13C1 |
| Uniprot No | Q8NE31 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-585aa |
| 氨基酸序列 | MFSCFCFSLQDNSFSSTTVTECDEDPVSLHEDQTDCSSLRDENNKENYPDAGALVEEHAPPSWEPQQQNVEATVLVDSVLRHSMGNFKSRKPKSIFKAESGRSHGESQETEHVVSSQSECQVRAGTPAHESPQNNAFKCQETVRLQPRIDQRTAISPKDAFETRQDLNEEEAAQVHGVKDPAPASTQSVLADGTDSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGDNPLLSPRCSIFSQSQRFNLDPESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPRENGKPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLPVGDHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI |
| 分子量 | 92.2 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人FAM13C1蛋白的3篇参考文献的简要总结(内容为模拟虚构，仅供参考)：
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1. **文献名称**: *"Functional Analysis of Recombinant Human FAM13C1 in Airway Epithelial Cells"*
**作者**: Smith A, et al.
**摘要**: 研究通过大肠杆菌系统表达重组人FAM13C1蛋白，探究其在气道上皮细胞中的磷酸酶活性及与慢性阻塞性肺疾病(COPD)的关联。结果显示，FAM13C1通过调控Wnt/β-catenin信号通路影响细胞增殖。
2. **文献名称**: *"Structural Characterization of FAM13C1 and Its Role in Lung Cancer"*
**作者**: Lee B, Chen X.
**摘要**: 利用杆状病毒-昆虫细胞系统重组表达FAM13C1蛋白，解析其晶体结构，发现其C端结构域参与肺癌细胞迁移和侵袭，可能成为潜在治疗靶点。
3. **文献名称**: *"Recombinant FAM13C1 Modulates Lipid Metabolism in Hepatocytes"*
**作者**: Wang Y, et al.
**摘要**: 通过哺乳动物HEK293细胞表达重组FAM13C1.证实其与脂代谢相关蛋白PPARγ互作，调节肝脏脂质堆积，为代谢综合征研究提供新方向。
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注：若需真实文献，建议在 **PubMed** 或 **Google Scholar** 搜索关键词 "recombinant FAM13C1" 或 "FAM13C1 protein function" 获取最新研究。
Recombinant human FAM13C1 protein is a genetically engineered form of the FAM13C1 (family with sequence similarity 13 member C1) protein, which belongs to the FAM13 family implicated in cellular signaling and metabolic regulation. FAM13C1 contains conserved domains, including a conserved region in its N-terminus and a duplicated phosphatase 1 regulatory subunit-like domain, though its precise molecular function remains under investigation. Studies suggest its involvement in cell proliferation, apoptosis, and intracellular trafficking, with potential roles in lipid metabolism and immune response modulation.
This recombinant protein is typically produced using expression systems like *E. coli* or mammalian cells, enabling standardized study of its interactions, post-translational modifications, and structure-function relationships. Its recombinant form facilitates in vitro assays, antibody development, and drug screening. FAM13C1 has garnered interest due to its association with human diseases. Genome-wide association studies (GWAS) link FAM13C1 variants to chronic obstructive pulmonary disease (COPD), lung cancer susceptibility, and metabolic disorders. Its overexpression in certain cancers correlates with tumor progression, suggesting therapeutic targeting potential. However, mechanistic insights into its pathophysiology remain limited, necessitating further research to elucidate its biological pathways and clinical relevance. The availability of recombinant FAM13C1 accelerates functional studies, aiding the exploration of its role in health and disease.
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