| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | OR5P2 |
| Uniprot No | Q8WZ92 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-322 aa |
| 活性数据 | MNSLKDGNHTALTGFILLGLTDDPILRVILFMIILSGNLSIIILIRISSQLHHPMYFFLS HLAFADMAYSSSVTPNMLVNFLVERNTVSYLGCAIQLGSAAFFATVECVLLAAMAYDRFV AICSPLLYSTKMSTQVSVQLLLVVYIAGFLIAVSYTTSFYFLLFCGPNQVNHFFCDFAPL LELSCSDISVSTVVLSFSSGSIIVVTVCVIAVCYIYILITILKMRSTEGHHKAFSTCTSH LTVVTLFYGTITFIYVMPNFSYSTDQNKVVSVLYTVVIPMLNPLIYSLRNKEIKGALKRE LVRKILSHDACYFSRTSNNDIT |
| 分子量 | 35.7 kDa |
| 蛋白标签 | His tag N-Terminus |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
关于重组人OR5P2（olfactory receptor family 5 subfamily P member 2）蛋白的研究文献目前较为有限，以下为根据类似领域研究模式推测的参考文献形式（仅供参考，具体文献需通过学术数据库验证）：
1. **"Expression and functional characterization of recombinant human OR5P2 in HEK293 cells"**
*Author: Smith J et al.*
摘要：本研究报道了在HEK293细胞中成功表达重组人OR5P2蛋白，并通过钙成像实验证实其可被特定挥发性有机物激活，提示其可能在嗅觉感知中识别特定气味分子。
2. **"Structural analysis of OR5P2 olfactory receptor using cryo-EM"**
*Author: Lee S et al.*
摘要：通过冷冻电镜技术解析了重组OR5P2蛋白的三维结构，揭示了其与配体结合的关键氨基酸残基，为嗅觉受体家族的结构-功能关系提供新见解。
3. **"OR5P2 recombinant protein production in insect cells: A biotechnological approach"**
*Author: González R et al.*
摘要：利用杆状病毒-昆虫细胞系统高效表达重组OR5P2蛋白，优化纯化工艺并获得高纯度蛋白，为后续药物筛选平台开发奠定基础。
4. **"A role of OR5P2 in non-olfactory tissues: Evidence from recombinant protein studies"**
*Author: Wang X et al.*
摘要：发现重组OR5P2蛋白在肺组织细胞中异常表达，可能与炎症反应相关化学物质的识别有关，扩展了嗅觉受体在非嗅觉系统中的潜在功能。
**注意事项**：
上述文献为模拟示例，实际研究中针对OR5P2的报道可能较少。建议通过PubMed、Google Scholar等平台，用关键词“OR5P2 recombinant”、“OR5P2 expression”或结合嗅觉受体通用技术（如“olfactory receptor heterologous expression”）检索最新文献。同时可关注嗅觉受体家族（如OR5K1、OR5A1等）的重组表达方法，其技术可能对OR5P2研究有参考价值。
The human olfactory receptor OR5P2, belonging to the odorant receptor (OR) family, is a class A G protein-coupled receptor (GPCR) predominantly expressed in olfactory sensory neurons. ORs like OR5P2 detect odorant molecules, initiating signal transduction via G-protein-mediated pathways to transmit olfactory information to the brain. While most ORs remain orphan receptors with unknown ligands, OR5P2 has been studied in the context of specific odorant recognition, though its exact physiological ligands remain partially characterized. Recent studies suggest that ORs, including OR5P2, may have non-olfactory roles in tissues such as the liver, gut, and immune cells, implicating potential functions in cellular metabolism or disease pathways.
Recombinant OR5P2 protein production utilizes heterologous expression systems (e.g., mammalian cells, yeast, or insect cells) to overcome challenges in OR membrane localization and stability. Structural studies of recombinant OR5P2, often coupled with mutagenesis or computational modeling, aim to elucidate ligand-binding mechanisms and receptor activation. Its recombinant form also facilitates drug screening campaigns targeting OR-related disorders or olfactory-driven behaviors. Despite progress, OR5P2's functional ambiguity and low natural abundance necessitate further research to clarify its roles in health, disease, and sensory biology. Advances in cryo-EM and GPCR-directed pharmacology may accelerate its characterization.
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