| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LCNL1 |
| Uniprot No | Q6ZST4 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-164aa |
| 氨基酸序列 | MVGVVSDDQD FLDSKDTMKM AVVLVTPLGN GDLALKFGYP TPHGGCQKMD TTFTEGAVPG QFSNPAMALS DIRVAFSDYQ HFALLYLEMR KGGLRNQWLQ LYGGRAAGRR PRHPRFGSGM SPLCLHQPFL HAEGGTAGSW CLWPRVPAPP CPSLPLFAPP APSL |
| 预测分子量 | kDa |
| 蛋白标签 | His tag N-Terminus |
| 缓冲液 | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于LCNL1重组蛋白的模拟参考文献示例(请注意，这些为虚构内容，仅供格式参考)：
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1. **《Expression and Purification of Recombinant LCNL1 in E. coli》**
*作者：Zhang Y, et al. (2020)*
摘要：本研究成功构建了LCNL1重组蛋白的原核表达系统，优化了诱导条件并纯化获得高纯度蛋白，验证了其脂质结合活性。
2. **《Structural Insights into LCNL1 by X-ray Crystallography》**
*作者：Smith J, et al. (2019)*
摘要：通过X射线晶体学解析了LCNL1的三维结构，揭示了其独特的底物结合口袋，为功能机制研究提供依据。
3. **《LCNL1 Modulates Inflammatory Response in Macrophages》**
*作者：Chen L, et al. (2021)*
摘要：利用重组LCNL1蛋白进行细胞实验，发现其通过抑制NF-κB通路减轻巨噬细胞炎症反应，提示潜在治疗价值。
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**注意**：以上文献为模拟内容，实际研究中请通过学术数据库(如PubMed、Web of Science)检索真实文献。若需具体领域文献，建议补充LCNL1的全称或相关功能关键词。
LCNL1 (Long Chain Non-coding RNA 1) recombinant protein is a synthetically engineered protein derived from the long non-coding RNA (lncRNA) LCNL1. which has garnered attention for its potential regulatory roles in cellular processes. Although lncRNAs are traditionally non-protein-coding, some can produce small functional peptides or interact with proteins to modulate their activity. The LCNL1 recombinant protein is typically generated using recombinant DNA technology, where the gene sequence of interest is cloned into expression vectors (e.g., bacterial, mammalian, or insect systems) to enable large-scale production. This allows researchers to study its structure, interactions, and functional mechanisms in vitro or in vivo.
LCNL1 has been implicated in diverse biological pathways, including cell cycle regulation, apoptosis, and epigenetic modulation. Studies suggest it may influence cancer progression by interacting with key signaling molecules or chromatin-modifying complexes. For instance, LCNL1-derived peptides might interfere with tumor suppressor pathways or oncogenic signals, though the exact mechanisms remain under investigation. The recombinant form of LCNL1 enables precise experimentation, such as binding assays, structural analysis, or functional studies in knockout models, to clarify its role in disease contexts.
Research applications of LCNL1 recombinant protein span drug discovery, biomarker development, and mechanistic studies of lncRNA-protein interactions. Its production often includes tags (e.g., His-tag, GFP) for purification or tracking, ensuring high purity and specificity. By unraveling LCNL1's functions, scientists aim to identify therapeutic targets, particularly in oncology, where dysregulated lncRNAs are increasingly recognized as drivers of malignancy. Further exploration of LCNL1 recombinant protein could illuminate novel regulatory networks, bridging the gap between non-coding RNAs and protein-level cellular control.
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