| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | CGR11 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human CGREF1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于CGREF1抗体的假设性参考文献示例(注：以下内容为虚构，仅供格式参考)：
1. **文献名称**：CGREF1 regulates cellular growth via TGF-β signaling in colorectal cancer
**作者**：Li X, Zhang Y, et al.
**摘要**：本研究利用CGREF1特异性抗体，通过免疫沉淀和Western blot技术，发现CGREF1通过结合TGF-β受体调控结直肠癌细胞增殖，并揭示其作为肿瘤抑制因子的潜在机制。
2. **文献名称**：Expression profiling of CGREF1 in neural development using a novel monoclonal antibody
**作者**：Wang H, et al.
**摘要**：开发了一种高特异性抗CGREF1单克隆抗体，通过免疫组化分析发现CGREF1在小鼠大脑皮层发育中高表达，提示其参与神经元迁移和突触形成。
3. **文献名称**：CGREF1 interacts with mTOR pathway components: Insights from co-immunoprecipitation assays
**作者**：Chen J, et al.
**摘要**：通过CGREF1抗体介导的共免疫沉淀实验，证实CGREF1与mTORC1复合物存在物理相互作用，可能介导营养应激条件下的细胞代谢重编程。
4. **文献名称**：A peptide-based CGREF1 antibody enhances sensitivity in circulating tumor cell detection
**作者**：Kim S, et al.
**摘要**：报道了一种基于抗原表位的CGREF1多克隆抗体，优化后应用于液体活检技术，显著提高了对乳腺癌患者循环肿瘤细胞的检测灵敏度。
(注：以上文献及内容均为示例，实际研究中需通过PubMed等数据库查询真实文献。)
The CGREF1 (Cell Growth and Repair-Enhancing Factor 1) antibody is a research tool designed to detect and study the CGREF1 protein, which is implicated in cellular growth, tissue repair, and regeneration processes. CGREF1. also known as CGRF1. is a secreted protein encoded by the CGREF1 gene, primarily expressed in the brain, kidneys, and other tissues. It plays a role in modulating cell proliferation, differentiation, and survival, particularly in neural and epithelial cells. Studies suggest its involvement in neuroprotection, wound healing, and cancer progression, where dysregulated expression may influence tumorigenesis or tissue repair efficiency.
The CGREF1 antibody, typically developed in rabbit or mouse models, enables researchers to investigate protein localization, expression levels, and interaction partners via techniques like Western blotting, immunohistochemistry, and immunofluorescence. Its applications extend to exploring CGREF1's functional mechanisms in disease models, such as neurodegenerative disorders, renal injury, or cancers. Validation data, including knockout controls and specificity assays, are critical to ensure reliable detection. Commercial availability and custom production options facilitate its use in both basic and translational research, aiding the development of therapeutic strategies targeting CGREF1-related pathways.
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