| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/20-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | TRAMP |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human DPT |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于DPT(白喉、百日咳、破伤风)疫苗抗体研究的3篇示例文献(模拟摘要，非真实文献，仅供参考)：
1. **文献名称**：*Long-term persistence of antibodies after DTP vaccination in children*
**作者**：Smith J, et al.
**摘要**：研究追踪儿童接种DTP疫苗后抗体水平的长期变化，发现白喉和破伤风抗体可持续10年以上，而百日咳抗体在5年后显著下降，提示需加强免疫策略。
2. **文献名称**：*Comparison of cellular and acellular DTP vaccines on antibody response*
**作者**：Li X, et al.
**摘要**：对比全细胞与无细胞DTP疫苗的免疫效果，发现无细胞疫苗诱导的百日咳抗体水平较低，但不良反应更少，建议优化接种方案平衡安全性与有效性。
3. **文献名称**：*Maternal DTP antibodies and infant immunity: A cohort study*
**作者**：Garcia M, et al.
**摘要**：分析母亲DTP抗体经胎盘传递对婴儿保护作用，发现高母体抗体水平可降低新生儿感染风险，但可能干扰婴儿自身疫苗接种效果。
如需具体文献，建议通过PubMed或Google Scholar搜索关键词“DTP vaccine antibody persistence”、“Diphtheria-tetanus-pertussis immune response”获取最新研究。
DPT antibodies target dermatopontin, a multifunctional extracellular matrix (ECM) protein encoded by the *DPT* gene. Dermatopontin plays a critical role in ECM organization, cell-matrix interactions, and tissue homeostasis. It binds to collagen, fibronectin, and decorin, facilitating collagen fibrillogenesis and promoting ECM stability. Additionally, it modulates TGF-β signaling, influencing cell adhesion, proliferation, and wound healing. Dysregulation of dermatopontin has been linked to fibrotic disorders, skin diseases, and cancer progression, where altered ECM remodeling is a hallmark.
DPT antibodies are essential tools for studying dermatopontin's expression, localization, and functional roles in both physiological and pathological contexts. They are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to assess protein levels in tissues or cell cultures. In research, these antibodies help elucidate mechanisms underlying fibrosis, tumor microenvironment modulation, and connective tissue disorders. Commercially available DPT antibodies are typically raised in hosts like rabbits or mice, with validation for specificity across human, mouse, and rat samples. Their applications extend to diagnostic exploration, particularly in diseases characterized by ECM abnormalities, making them valuable for both basic research and potential therapeutic development.
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