Rabbit Polyclonal TPST1 Antibody

The tyrosylprotein sulfotransferase 1 (TPST1) antibody is a tool used to detect and study TPST1. an enzyme critical for post-translational tyrosine sulfation. TPST1. located in the trans-Golgi network, catalyzes the transfer of sulfate groups to tyrosine residues in secretory and membrane proteins, modulating their interactions in processes like coagulation, inflammation, and receptor signaling. Dysregulation of TPST1 has been linked to diseases such as cancer, cardiovascular disorders, and immune dysfunction. Antibodies targeting TPST1 enable researchers to investigate its expression, localization, and functional roles in both physiological and pathological contexts. These antibodies are widely applied in techniques like Western blotting, immunohistochemistry, and immunofluorescence. Recent studies highlight TPST1's involvement in tumor progression, angiogenesis, and metabolic pathways, making its antibody a valuable reagent for mechanistic and therapeutic exploration. Commercial TPST1 antibodies are typically validated for specificity across human and model organisms, though variability in sensitivity may require optimization. Ongoing research aims to clarify TPST1's regulatory networks and its potential as a biomarker or drug target.