| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | DDX26 |
| Uniprot No | Q9UL03 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 779-887aa |
| 氨基酸序列 | DKEQCAEENIPASSLNKGKKLMHCRSHEEVNTELKAQIMKEIRKPGRKYERIFTLLKHVQGSLQTRLIFLQNVIKEASRFKKRMLIEQLENFLDEIHRRANQINHINSN |
| 分子量 | 37.73 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人DDX26蛋白的模拟参考文献(仅供参考，实际文献可能存在差异)：
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1. **文献名称**：*"Functional Characterization of Recombinant Human DDX26B in RNA Helicase Activity"*
**作者**：Suzuki M, et al.
**摘要**：研究报道了人源DDX26B蛋白的重组表达及纯化，验证其ATP依赖的RNA解旋酶活性，并发现其在核糖体RNA加工中的潜在作用。
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2. **文献名称**：*"DDX26. a DEAD-box Protein, Interacts with Influenza Virus NS1 Protein and Modulates Viral Replication"*
**作者**：Wang X, et al.
**摘要**：通过重组人DDX26蛋白与流感病毒NS1蛋白的相互作用实验，揭示了DDX26在病毒复制周期中的调控功能，表明其可能成为抗病毒靶点。
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3. **文献名称**：*"Recombinant DDX26 Suppresses Tumor Growth by Regulating Alternative Splicing in Hepatocellular Carcinoma"*
**作者**：Li Y, et al.
**摘要**：利用重组DDX26蛋白进行体外实验，发现其通过调控mRNA剪接抑制肝癌细胞增殖，为癌症治疗提供了新思路。
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4. **文献名称**：*"Crystallization and Structural Analysis of Recombinant Human DDX26 Protein"*
**作者**：Thompson JR, et al.
**摘要**：报道了重组DDX26蛋白的晶体结构解析，揭示了其DEAD-box结构域的关键功能位点，为后续药物设计奠定基础。
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**注意**：以上内容为模拟生成的文献，实际研究中请通过学术数据库(如PubMed、Web of Science)以“DDX26”、“recombinant DDX26”等关键词检索真实文献。
Recombinant human DDX26 protein is a genetically engineered variant of the DEAD-box helicase family member DDX26 (also known as DDX26B or DKFZP434L187), which plays a role in RNA metabolism and cellular processes. DEAD-box proteins are RNA helicases involved in RNA unwinding, splicing, translation, and ribosome biogenesis. DDX26 is characterized by its conserved DEAD (Asp-Glu-Ala-Asp) motif, which is critical for ATP-dependent RNA binding and unwinding activities. While the exact biological functions of DDX26 remain less characterized compared to other DEAD-box proteins, studies suggest its involvement in RNA processing, transcriptional regulation, and potential roles in viral replication or stress responses. It is expressed in various tissues, with higher levels observed in the testis, brain, and immune cells. Recombinant DDX26 is produced using prokaryotic (e.g., E. coli) or eukaryotic expression systems to ensure proper folding and post-translational modifications. It serves as a tool for in vitro studies to dissect its enzymatic activity, RNA-protein interactions, and role in diseases such as cancer or neurodevelopmental disorders. Research on DDX26 is ongoing to elucidate its specific molecular mechanisms and therapeutic potential.
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