| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | FAM115C |
| Uniprot No | A6NFQ2 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-845aa |
| 氨基酸序列 | MATIAAAAFEALMDGVTCWDVPRGPIPSELLLIGEAAFPVMVNDKGQVLIAASSYGRGRLVVVSHEGYLSHAGLAPFLLNAVSWLCPCPGAPVGVHPSLAPLVNILQDAGLEAQVKPEPGEPLGVYCINAYNDTLTATLIQFVKHGGGLLIGGQAWYWASQHGPDKVLSRFPGNKVTSVAGVYFTDTYGDRDRFKVSKKVPKIPLHVRYGEDVRQDQQQLLEGISELDIRTGGVPSQLLVHGALAFPLGLDASLNCFLAAAHYGRGRVVLAAHECLLCAPKMGPFLLNAVRWLARGQTGKVGVNTNLKDLCPLLSEHGLQCSLEPHLNSDLCVYCCKAYSDKEAKQLQEFVAEGGGLLIGGQAWWWASQNPGHCPLAGFPGNIILNCFGLSILPQTLKAGCFPVPTPEMRSYHFRKALSQFQAILNHENGNLEKSCLAKLRVDGAAFLQIPAEGVPAYISLHRLLRKMLRGSGLPAVSRENPVASDSYEAAVLSLATGLAHSGTDCSQLAQGLGTWTCSSSLYPSKHPITVEINGINPGNNDCWVSTGLYLLEGQNAEVSLSEAAASAGLRVQIGCHTDDLTKARKLSRAPVVTHQCWMDRTERSVSCLWGGLLYVIVPKGSQLGPVPVTIRGAVPAPYYKLGKTSLEEWKRQMQENLAPWGELATDNIILTVPTTNLQALKDPEPVLRLWDEMMQAVARLAAEPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVKEIINEMDMRSRGVWGPIHELGHNQQRHGWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHEALSPPERERRIKAHLGKGAPLCDWNVWTALETYLQVLSRNSGRRG |
| 分子量 | 119.35 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下为关于重组人FAM115C蛋白的虚构参考文献(供示例参考，实际文献需自行核实)：
1. **文献名称**: "Structural Characterization of Recombinant Human FAM115C and Its Role in Cellular Apoptosis"
**作者**: Smith J, et al.
**摘要**: 解析重组人FAM115C蛋白的晶体结构，发现其通过调控Bcl-2家族蛋白参与线粒体凋亡通路，可能作为肿瘤治疗靶点。
2. **文献名称**: "FAM115C Functions as a Tumor Suppressor via Modulating Wnt/β-catenin Signaling"
**作者**: Chen L, et al.
**摘要**: 重组FAM115C过表达抑制结肠癌细胞增殖，实验表明其通过结合β-catenin并促进其降解，从而抑制Wnt信号通路活性。
3. **文献名称**: "Recombinant FAM115C Protein Inhibits Hepatitis B Virus Replication by Interacting with Viral Core Protein"
**作者**: Zhang Y, et al.
**摘要**: 体外实验证明重组FAM115C可与乙肝病毒核心蛋白结合，抑制病毒复制，提示其在抗病毒治疗中的潜在应用。
4. **文献名称**: "Expression and Purification of Recombinant Human FAM115C: Insights into Its Post-Translational Modifications"
**作者**: Wang R, et al.
**摘要**: 开发重组FAM115C的大肠杆菌表达系统，并鉴定其磷酸化修饰位点，为功能研究提供高质量蛋白样品。
**注意**：以上为模拟生成的参考文献，实际文献需通过PubMed、Google Scholar等平台检索确认。
**Background of Recombinant Human FAM115C Protein**
FAM115C (Family with sequence similarity 115 member C) is a poorly characterized protein encoded by the *FAM115C* gene, located on human chromosome 9. Although its exact biological function remains unclear, FAM115C is hypothesized to play roles in cellular processes such as cell cycle regulation, DNA repair, or apoptosis, based on limited studies and sequence homology with other proteins. Structurally, it contains conserved domains associated with protein-protein interactions, suggesting potential involvement in signaling pathways or molecular scaffolding.
Recombinant human FAM115C protein is artificially produced using expression systems like *E. coli* or mammalian cells to enable functional and structural studies. Purification typically involves affinity chromatography tags (e.g., His-tag) for high-yield isolation. Current research focuses on elucidating its interactome, post-translational modifications (e.g., phosphorylation), and relevance to diseases. Preliminary data link FAM115C to cancer progression, though mechanistic insights are lacking.
Interest in recombinant FAM115C stems from its potential as a biomarker or therapeutic target, particularly in oncology. Its study could uncover novel pathways in cellular homeostasis or stress responses. However, significant gaps persist in understanding its precise molecular mechanisms, tissue-specific expression, and physiological relevance. Further biochemical and in vivo analyses are required to define its role in health and disease.
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