关键信息
-
基因名
MRPS18B
- 应用
-
别名
Small ribosomal subunit protein mS40. 28S ribosomal protein S18-2. mitochondrial. MRP-S18-2. 28S ribosomal protein S18b. mitochondrial. MRP-S18-b. Mrps18-b. S18mt-b. Small ribosomal subunit protein bS18b
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9Y676
-
表达区间
1-258 aa
-
氨基酸序列
MAASVLNTVLRRLPMLSLFRGSHRVQVPLQTLCTKAPSEEDSLSSVPISPYKDEPWKYLESEEYQERYGSRPVWADYRRNHKGGVPPQRTRKTCIRRNKVVGNPCPICRDHKLHVDFRNVKLLEQFVCAHTGIIFYAPYTGVCVKQHKRLTQAIQKARDHGLLIYHIPQVEPRDLDFSTSHGAVSATPPAPTLVSSDPWYPWYNWKQPPERELSRLRRLYQGHLQEESGPPPESMPKMPPRTPAEASSTGQTGPQSAL
-
分子量
54.12 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MRPS18B, a member of the mitochondrial ribosomal protein S18 family, plays a crucial role in mitochondrial biogenesis and protein synthesis, thus impacting crucial cellular processes such as energy production and apoptosis. Research indicates that MRPS18B is involved in mitochondrial translation, which is essential for the proper functioning of the mitochondria, the powerhouse of the cell. Dysregulation of MRPS18B has been linked to various pathological conditions, including neurodegenerative diseases and cancer, further underscoring its biological significance. Recent studies have focused on the recombinant expression of MRPS18B to explore its functional mechanisms and interactions within the mitochondrial ribosome, enabling the investigation of its role in mitochondrial disorders. The development of MRPS18B recombinant protein provides valuable insights into its structure-function relationship and offers potential for therapeutic applications, particularly in targeting mitochondrial dysfunction. Understanding the precise mechanisms by which MRPS18B operates could lead to novel strategies in the treatment of diseases associated with mitochondrial impairment, making it a promising target for future research in cellular bioenergetics and metabolic regulation.
