关键信息
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基因名
ANKRD16
- 应用
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别名
Ankrd16; Ankyrin repeat domain 16; Ankyrin repeat domain-containing Protein 16; ANR16_HUMAN; DKFZP434N1511
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6P6B7
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表达区间
1-361aa
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氨基酸序列
MAQPGDPRRL CRLVQEGRLR ALKEELQAAG GCPGPAGDTL LHCAARHGHR DVLAYLAEAW GMDIEATNRD YKRPLHEAAS MGHRDCVRYL LGRGAAVDCL KKADWTPLMM ACTRKNLGVI QELVEHGANP LLKNKDGWNS FHIASREGDP LILQYLLTVC PGAWKTESKI RRTPLHTAAM HGHLEAVKVL LKRCQYEPDY RDNCGVTALM DAIQCGHIDV ARLLLDEHGA CLSAEDSLGA QALHRAAVTG QDEAIRFLVS ELGVDVDVRA TSTHLTALHY AAKEGHTSTI QTLLSLGADI NSKDEKNRSA LHLACAGQHL ACAKFLLQSG LKDSEDITGT LAQQLPRRAD VLQGSGHSAM T
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分子量
39.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
ANKRD16, a member of the ankyrin repeat domain family, has garnered significant interest in recent research due to its potential role in various cellular processes and disease mechanisms. This protein is characterized by a series of ankyrin repeat motifs, which are known to mediate protein-protein interactions, thus contributing to cellular signaling, cytoskeletal organization, and transcriptional regulation. Studies have suggested that ANKRD16 may be involved in the regulation of immune responses and inflammation, as well as in the modulation of cell proliferation and differentiation. Furthermore, its expression has been implicated in several pathologies, including cancer, where alterations in its function may influence tumorigenesis and metastasis. The recombinant production of ANKRD16 is crucial for elucidating its biological functions and interactions at a molecular level, enabling the development of targeted therapies. Researchers are actively investigating the structural characteristics of ANKRD16, employing techniques such as X-ray crystallography and NMR spectroscopy to uncover its functional dynamics. This research is expected to provide insights into the therapeutic potential of modulating ANKRD16 activity in various diseases, making it a promising target for future drug development.
