关键信息
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基因名
CDH6
- 应用
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别名
CDH6；Cadherin-6
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P55285
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表达区间
22-615aa
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氨基酸序列
TLSTPLSKRTSGFPAKKRALELSGNSKNELNRSKRSWMWNQFFLLEEYTG SDYQYVGKLHSDQDRGDGSLKYILSGDGAGDLFIINENTGDIQATKRLDR EEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTKEVYTATV PEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQPYFSVESETGIIK TALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRF PQSTYQFKTPESSPPGTPIGRIKASDADVGENAEIEYSITDGEGLDMFDV ITDQETQEGIITVKKLLDFEKKKVYTLKVEASNPYVEPRFLYLGPFKDSA TVRIVVEDVDEPPVFSKLAYILQIREDAQINTTIGSVTAQDPDAARNPVK YSVDRHTDMDRIFNIDSGNGSIFTSKLLDRETLLWHNITVIATEINNPKQ SSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQTLHAVDKDDPY SGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLPV VISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGAVDH HHHHH
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分子量
67 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CDH6, or Cadherin 6, is a member of the cadherin family of proteins, which are crucial for cell adhesion and various developmental processes. Cadherins play vital roles in maintaining tissue integrity and facilitating intercellular communication. CDH6, specifically, is predominantly expressed in the developing neural tissues and has been implicated in processes such as neuronal development and the organization of the nervous system. In recent years, research has increasingly focused on the role of CDH6 in various pathologies, including tumors and neurodevelopmental disorders, making it a target of interest for therapeutic interventions. The recombinant protein of CDH6 can be produced for various applications, including studying its structural properties, understanding its interactions with other proteins, and evaluating its potential role in disease mechanisms. Additionally, the insights gained from CDH6 recombinant protein studies can help in drug development, as targeting specific cadherin interactions may offer novel strategies for treating conditions where cell adhesion mechanisms are disrupted. Overall, the characterization and study of CDH6 recombinant protein hold significant promise for advancing our knowledge of cellular adhesion processes and their implications in health and disease.
