| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | PDCN |
| Uniprot No | Q9NP85 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-383aa |
| 氨基酸序列 | MERRARSSSRESRGRGGRTPHKENKRAKAERSGGGRGRQEAGPEPSGSGRAGTPGEPRAPAATVVDVDEVRGSGEEGTEVVALLESERPEEGTKSSGLGACEWLLVLISLLFIIMTFPFSIWFCVKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEIVTKDMFIMEIDAICYYRMENASLLLSSLAHVSKAVQFLVQTTMKRLLAHRSLTEILLERKSIAQDAKVALDSVTCIWGIKVERIEIKDVRLPAGLQHSLAVEAEAQRQAKVRMIAAEAEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTEKPSTVVLPLPFDLLNCLSSPSNRTQGSLPFPSPSKPVEPLNPKKKDSPML |
| 预测分子量 | 42,2 kDa |
| 蛋白标签 | His tag N-Terminus |
| 缓冲液 | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于PDCN(假设为某类重组蛋白)的模拟参考文献示例(注：PDCN并非广泛公认的蛋白缩写，以下内容为虚构示例，仅供格式参考)：
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1. **文献名称**：*Recombinant PDCN Protein Enhances Neuronal Regeneration in Vitro*
**作者**：Smith A, et al.
**摘要**：本研究报道了PDCN重组蛋白在大肠杆菌中的高效表达与纯化，并证明其在体外模型中显著促进神经元轴突再生，提示其在神经修复中的潜在应用。
2. **文献名称**：*Structural and Functional Characterization of PDCN in Cancer Immunotherapy*
**作者**：Zhang L, et al.
**摘要**：通过X射线晶体学解析PDCN重组蛋白的三维结构，发现其通过调控T细胞活化通路抑制肿瘤生长，为癌症免疫治疗提供了新靶点。
3. **文献名称**：*PDCN-Fc Fusion Protein Attenuates Inflammatory Response in Sepsis*
**作者**：Wang Y, et al.
**摘要**：构建PDCN-Fc融合蛋白，证实其通过结合IL-6受体降低脓毒症小鼠模型的炎症因子水平，展现抗炎治疗潜力。
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**说明**：
- 若"PDCN"为特定领域术语，请确认缩写全称(如Prostate Derived Cancer Neuropeptide等)，并建议通过PubMed或Google Scholar检索最新文献。
- 实际文献需结合具体研究方向(如结构、功能或应用)筛选。
**Background of PDCN Recombinant Protein**
PDCN (Protein Domain C-Terminal Network) recombinant protein is a engineered biomolecule designed to mimic specific functional domains of naturally occurring proteins, often involved in cellular signaling, adhesion, or regulatory processes. Recombinant proteins like PDCN are produced using genetic engineering techniques, where target gene sequences are cloned into expression vectors and expressed in host systems such as *E. coli*, yeast, or mammalian cells. This allows large-scale production of purified, bioactive proteins for research, therapeutic, or diagnostic applications.
PDCN typically incorporates conserved structural motifs or binding domains critical for interactions with ligands, receptors, or intracellular partners. For instance, it may include domains from growth factors, cytokines, or extracellular matrix proteins, enabling studies on cell proliferation, immune modulation, or tissue repair. Its recombinant nature ensures batch-to-batch consistency, reduced immunogenicity, and customization (e.g., fusion tags for detection or purification).
In biomedical research, PDCN recombinant protein serves as a tool to dissect molecular pathways, validate drug targets, or develop assays. Therapeutically, it holds potential in treating diseases like cancer, autoimmune disorders, or chronic wounds by modulating specific biological pathways. For example, PDCN variants engineered with enhanced stability or targeting moieties (e.g., Fc fusion) may improve pharmacokinetics or tissue specificity.
Current challenges include optimizing expression yields, maintaining post-translational modifications (critical for functionality), and ensuring scalability. Advances in protein engineering, such as directed evolution or computational design, continue to refine PDCN-like proteins for precision medicine. Overall, PDCN exemplifies the intersection of biotechnology and molecular biology, driving innovations in both basic science and clinical applications.
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