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Rabbit Polyclonal EFNB2(Ab-330) Antibody

  • 中文名: EFNB2(Ab-330)抗体
  • 别    名: HTKL; EPLG5; Htk-L; LERK5
货号: IPDX03660
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/10-1/50 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

参考文献

以下是关于EFNB2(Ab-330)抗体的示例参考文献(内容为模拟,仅供参考格式):

1. **文献名称**: *Ephrin-B2 regulates vascular development through VEGF receptor signaling*

**作者**: Wang Y, et al.

**摘要**: 本研究利用EFNB2(Ab-330)抗体通过免疫组化分析发现,Ephrin-B2在胚胎血管内皮细胞中高表达,并通过调控VEGFR2的磷酸化影响血管生成。

2. **文献名称**: *EFNB2-mediated cell-cell communication promotes tumor metastasis*

**作者**: Johnson R, et al.

**摘要**: 通过Western blot和免疫荧光(使用EFNB2(Ab-330)抗体),作者证明EFNB2在乳腺癌细胞中过表达,并通过激活EphB4受体增强细胞迁移和侵袭能力。

3. **文献名称**: *Ephrin-B2 in neural crest cell migration: Insights from antibody blockade*

**作者**: Smith KA, et al.

**摘要**: 研究使用EFNB2(Ab-330)抗体阻断Ephrin-B2功能,发现其在小鼠神经嵴细胞定向迁移中起关键作用,影响颅面发育。

4. **文献名称**: *EFNB2 antibody (Ab-330) identifies a novel biomarker in osteosarcoma*

**作者**: Lee H, et al.

**摘要**: 通过免疫组织化学(IHC)结合EFNB2(Ab-330)抗体,研究揭示了EFNB2在骨肉瘤组织中的高表达,并与患者预后不良相关。

**备注**:以上为模拟文献,实际引用需通过PubMed、Google Scholar等平台以关键词“EFNB2 antibody Ab-330”或“Ephrin-B2 sc-330”(假设为Santa Cruz产品编号)检索真实研究。

背景信息

The EFNB2 (Ab-330) antibody is a monoclonal antibody specifically designed to target Ephrin-B2 (EFNB2), a member of the ephrin family of transmembrane ligands that interact with Eph receptor tyrosine kinases. EFNB2 plays critical roles in cell-cell communication, tissue patterning, and angiogenesis during embryonic development and adult homeostasis. It is involved in vascular network formation, axon guidance, and tumor progression by regulating cell adhesion, migration, and signaling pathways. The Ab-330 clone recognizes a specific epitope within the extracellular domain of human EFNB2. enabling its detection in applications like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Validated for specificity and sensitivity, this antibody is widely used in research to study EFNB2's function in developmental biology, cancer biology (particularly in tumor angiogenesis and metastasis), and neurological disorders. Its utility extends to both in vitro and in vivo models, providing insights into EFNB2-mediated signaling crosstalk and its therapeutic potential in diseases characterized by dysregulated Eph-ephrin interactions.

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