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Rabbit Polyclonal ZADH2 Antibody

  • 中文名: ZADH2抗体
  • 别    名: nan
货号: IPDX03670
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/100-1/300 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 1/2000-1/5000 Human,Mouse,Rat

产品详情

参考文献

以下是关于ZADH2抗体的3篇模拟参考文献示例(注:因ZADH2相关研究较少,以下内容为假设性示例,实际文献需通过学术数据库核实):

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1. **文献名称**:ZADH2 as a Novel Biomarker in Hepatocellular Carcinoma: Antibody Development and Clinical Validation

**作者**:Chen L, et al.

**摘要**:本研究开发了针对ZADH2蛋白的高特异性单克隆抗体,证实ZADH2在肝癌组织中显著高表达,并与患者预后不良相关。抗体通过免疫组化验证,可用于肝癌诊断标志物检测。

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2. **文献名称**:Functional Role of ZADH2 in Cellular Redox Homeostasis Revealed by Antibody-Based Inhibition

**作者**:Wang Y, et al.

**摘要**:利用ZADH2抗体阻断其酶活性,发现ZADH2通过调节NAD+/NADH平衡影响细胞氧化应激反应,提示其在代谢性疾病中的潜在治疗靶点价值。

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3. **文献名称**:A Comparative Study of ZADH2 Antibody Specificity Across Species for Translational Research

**作者**:Smith J, et al.

**摘要**:评估了多种ZADH2抗体在小鼠、人类样本中的交叉反应性,确定了抗体#AB123在人类组织中的高特异性,为跨物种转化研究提供实验依据。

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**注意**:以上为模拟示例,真实文献需通过PubMed/Google Scholar检索。若研究较少,建议扩展检索关键词(如ZDH2、锌脱氢酶家族)或验证基因名称拼写(如是否涉及ZNF217等其他锌相关蛋白)。

背景信息

The ZADH2 antibody is a research tool designed to target the ZADH2 protein, a member of the zinc-containing alcohol dehydrogenase (ADH) family. ZADH2. also referred to as alcohol dehydrogenase 2 (ADH2) in some species, is an enzyme involved in oxidizing alcohols to aldehydes or ketones, playing a critical role in cellular detoxification and metabolic pathways. This protein is particularly noted for its activity in ethanol metabolism, lipid oxidation, and retinol processing, making it relevant in studies of liver function, cancer biology, and oxidative stress responses. The ZADH2 antibody is typically produced in host species like rabbits or mice using immunogenic peptide sequences derived from conserved regions of the protein. It is widely utilized in techniques such as Western blotting, immunohistochemistry, and immunofluorescence to detect ZADH2 expression levels, localization, and post-translational modifications in tissues or cell lines. Researchers employ this antibody to explore ZADH2's involvement in diseases like hepatocellular carcinoma, metabolic disorders, and alcohol-related pathologies. Validated for specificity through knockout controls or siRNA knockdown experiments, the ZADH2 antibody serves as a key reagent in elucidating the enzyme's regulatory mechanisms and its potential as a therapeutic or diagnostic target.

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