| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/300 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/10000 | Human,Mouse,Rat |
| Aliases | Proto-oncogene Mas, MAS1, MAS |
| Entrez GeneID | 4142 |
| WB Predicted band size | 37.5kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This MAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-314 amino acids from the C-terminal region of human MAS1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于SLC34A2抗体的参考文献示例(内容基于公开研究整理，非真实文献)：
1. **名称**：*SLC34A2 as a biomarker in pulmonary adenocarcinoma*
**作者**：Zhang Y, et al.
**摘要**：该研究通过免疫组化(使用SLC34A2特异性抗体)分析肺腺癌组织，发现SLC34A2蛋白高表达与患者预后不良相关，提示其可能作为治疗靶点。
2. **名称**：*Role of SLC34A2 in phosphate homeostasis*
**作者**：Itoh K, et al.
**摘要**：利用Western blot和免疫荧光(SLC34A2抗体)研究小鼠肠道组织，证实SLC34A2通过调控磷酸盐吸收维持体内平衡，基因敲除导致代谢异常。
3. **名称**：*SLC34A2 mutations in lung surfactant metabolism*
**作者**：Travis WD, et al.
**摘要**：通过抗体验证SLC34A2突变体蛋白在肺泡细胞中的表达缺失，发现其突变与肺表面活性物质代谢紊乱及新生儿呼吸窘迫综合征相关。
4. **名称**：*SLC34A2 antibody validation for diagnostic applications*
**作者**：Chen L, et al.
**摘要**：评估多种SLC34A2抗体的特异性与灵敏度，确定某克隆号抗体在病理切片中表现最佳，适用于肺癌的临床诊断。
(注：以上为模拟内容，实际文献需通过数据库检索确认。)
The solute carrier family 34 member 2 (SLC34A2) gene encodes a sodium-dependent phosphate transporter protein primarily expressed in lung, small intestine, kidney, and glandular tissues. It plays a critical role in phosphate homeostasis by mediating cellular uptake of inorganic phosphate. SLC34A2 is clinically significant due to its association with diseases such as pulmonary alveolar microlithiasis (PAM), a rare lung disorder caused by bi-allelic mutations, and its dysregulation in cancers like lung adenocarcinoma, where it may serve as a tumor-associated antigen.
SLC34A2 antibodies are immunological tools designed to detect and quantify the SLC34A2 protein in research and diagnostic contexts. These antibodies are widely used in techniques such as immunohistochemistry (IHC), immunofluorescence (IF), and Western blotting to study protein expression patterns, tissue localization, and pathological alterations. In cancer research, SLC34A2 antibodies help investigate its role in tumor progression, metastasis, and potential as a therapeutic target. Clinically, they aid in diagnosing SLC34A2-related disorders or identifying cancer biomarkers in tissue samples.
Validation of SLC34A2 antibodies is crucial, as cross-reactivity with other solute carriers or isoforms may occur. Reliable antibodies contribute to understanding SLC34A2's dual role in phosphate metabolism and disease pathogenesis, bridging basic research and clinical applications.
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