| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | UBAP-2 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human UBAP2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于UBAP2抗体的3篇示例参考文献(文献信息为虚构示例，实际引用请核实)：
1. **文献名称**：UBAP2 regulates cell proliferation in breast cancer via modulating ubiquitination
**作者**：Chen L, et al.
**摘要**：该研究利用UBAP2特异性抗体，发现UBAP2通过泛素化通路调控乳腺癌细胞中关键蛋白降解，促进肿瘤增殖和转移。
2. **文献名称**：UBAP2 antibody-based detection reveals its role in DNA damage response
**作者**：Wang Y, et al.
**摘要**：通过UBAP2抗体的免疫荧光实验，证明UBAP2在DNA损伤修复中与BRCA1复合物相互作用，影响基因组稳定性。
3. **文献名称**：Development of a monoclonal antibody against UBAP2 for diagnostic applications
**作者**：Kim S, et al.
**摘要**：研究团队开发了一种高特异性UBAP2单克隆抗体，验证其在结直肠癌组织中的过表达，提示其作为潜在生物标志物的价值。
注：以上文献为示例性内容，实际研究需查阅权威数据库(如PubMed)。建议结合具体研究领域补充关键词检索。
The UBAP2 (Ubiquitin-associated protein 2) antibody is a tool used to detect and study the UBAP2 protein, which plays a role in cellular processes linked to ubiquitination and protein degradation. UBAP2 is part of the ubiquitin-proteasome system, a critical pathway for maintaining protein homeostasis by tagging unwanted or damaged proteins for degradation. Research suggests UBAP2 may interact with ubiquitin or ubiquitin-like modifiers, potentially influencing protein quality control, cell cycle regulation, and stress responses. Its exact molecular mechanisms, however, remain under investigation.
UBAP2 antibodies are widely employed in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to analyze UBAP2 expression levels, localization, and interactions in various tissues or cell lines. Studies have explored its relevance in diseases such as cancer, where dysregulated ubiquitination pathways contribute to tumor progression. For instance, elevated UBAP2 expression has been observed in certain malignancies, hinting at its potential role as a biomarker or therapeutic target.
These antibodies are typically developed in hosts like rabbits or mice, with specificity validated through knockout controls or peptide blocking assays. Ongoing research aims to clarify UBAP2's functional diversity, including its involvement in RNA metabolism and cellular stress adaptation, underscoring its broader biological significance beyond protein degradation.
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