关键信息
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基因名
FABP7
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简介
FABP7 Protein, Human (His) expresses in E. coliwith a His tag. Fatty Acid-Binding Protein 7 (FABP-7) is one of the subtypes of FABPs and preferentially binds to n-3 and n-9 polyunsaturated fatty acids (PUFAs) such as docosahexaenotic acid (DHA) and oleic acid, respectively. FABP-7 is thought to be an important molecule for cell proliferation in healthy as well as diseased organisms[1].
- 应用
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别名
rHuFABP7, His; Fatty Acid-Binding Protein Brain; B-FABP; Brain-Type Fatty Acid-Binding Protein
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种属
Human
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表达系统
E. coli
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标签
N-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O15540-1
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表达区间
V2-A132
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蛋白长度
Full Length of Isoform-1
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分子量
16.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Fatty acid-binding protein 7 (FABP7), also known as brain FABP, is primarily expressed in the brain and plays a crucial role in the transport of fatty acids and influence on neurodevelopment. Its involvement in various physiological and pathological processes has garnered significant interest in recent years. Research has demonstrated that FABP7 is essential for neuronal differentiation, regulation of lipid metabolism, and maintenance of brain homeostasis. Notably, aberrations in FABP7 expression have been linked to neurodevelopmental disorders, including schizophrenia and autism spectrum disorders, highlighting its potential as a biomarker for these conditions. Moreover, FABP7 has been implicated in neuroinflammation and neurodegeneration, suggesting that it may serve as a therapeutic target in diseases such as Alzheimer's. The development of recombinant FABP7 proteins has facilitated in-depth studies of its structure-function relationships and interactions with fatty acids, paving the way for novel lipid-based therapies and interventions in neurodegenerative disorders. Understanding the biochemical pathways influenced by FABP7 could lead to innovative strategies for modulating its activity and addressing related neurological diseases. As the field continues to evolve, further exploration of FABP7’s role in brain function and pathology remains a promising avenue for research, with implications for both basic science and clinical applications.
