| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/20-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | HPF4; HTF1 |
| WB Predicted band size | 69 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide of human ZNF85 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于ZNF85抗体的3条模拟参考文献示例(请注意，以下内容为虚构，实际文献需通过学术数据库查询)：
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1. **文献名称**: "Characterization of ZNF85 Antibody for Detecting Human Zinc Finger Protein Expression in Cancer Cell Lines"
**作者**: Li, X. et al.
**摘要**: 本研究开发了一种高特异性ZNF85多克隆抗体，通过免疫印迹和免疫荧光验证其在多种癌细胞系中的表达，发现ZNF85在乳腺癌细胞中显著高表达，提示其可能参与肿瘤发生调控。
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2. **文献名称**: "ZNF85 Epitope Mapping and Antibody Validation in Neural Development Studies"
**作者**: Martinez, R. & Kim, S.
**摘要**: 文章报道了针对ZNF85蛋白C端结构域的单克隆抗体制备，并通过免疫组化证实其在小鼠胚胎神经组织中的特异性染色，为研究ZNF85在神经发育中的功能提供了工具。
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3. **文献名称**: "The Role of ZNF85 in Viral Infection: Insights from Antibody-Mediated Knockdown Experiments"
**作者**: Gupta, A. et al.
**摘要**: 利用ZNF85抗体进行功能阻断实验，发现ZNF85与宿主抗病毒反应相关基因的转录调控有关，提示其可能成为抗病毒治疗的潜在靶点。
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如需真实文献，建议通过 **PubMed** 或 **Google Scholar** 搜索关键词 "ZNF85 antibody" 或 "ZNF85 zinc finger protein" 获取最新研究。
The zinc finger protein 85 (ZNF85) belongs to the Krüppel-associated box (KRAB) domain-containing zinc finger protein family, a large group of transcription factors involved in gene regulation, chromatin remodeling, and epigenetic silencing. ZNF85 is characterized by multiple Cys2His2 (C2H2) zinc finger motifs, which mediate sequence-specific DNA binding, and a KRAB domain at its N-terminus that recruits corepressor complexes to suppress transcription. While its exact biological roles remain under investigation, ZNF85 is thought to participate in developmental processes, cell differentiation, and tumorigenesis due to its structural homology with other KRAB-ZNF proteins implicated in these functions.
Antibodies targeting ZNF85 are primarily used in research to study its expression patterns, subcellular localization, and interactions. They enable detection via techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Such tools have helped identify ZNF85's preferential expression in tissues like the brain, testis, and immune cells, suggesting tissue-specific regulatory roles. Additionally, studies link dysregulated ZNF85 expression to diseases, including certain cancers and neurodevelopmental disorders, though mechanistic insights are still emerging. Validation of ZNF85 antibodies typically includes knockout controls and specificity assays to ensure reliability in experimental models. These reagents remain critical for unraveling ZNF85's contributions to normal physiology and pathology.
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