Rabbit Polyclonal H1-2 Antibody

The H1-2 antibody is a monoclonal antibody primarily associated with research on influenza A viruses, particularly those expressing the hemagglutinin (HA) subtype H1. Hemagglutinin, a surface glycoprotein critical for viral entry into host cells, is a major target for neutralizing antibodies. The H1-2 antibody was developed to specifically recognize and bind conserved epitopes within the H1 HA subtype, which is historically significant due to its role in seasonal flu strains and past pandemics, such as the 2009 H1N1 pandemic. This antibody is often utilized in virological studies to investigate HA structure-function relationships, antigenic drift, and vaccine efficacy. Its specificity enables applications in immunoassays (e.g., ELISA, Western blot), immunohistochemistry, and flow cytometry for detecting H1-containing viral particles or infected cells. Additionally, H1-2 has been explored as a potential therapeutic candidate due to its ability to inhibit viral fusion or entry in preclinical models. Research into H1-2 also contributes to understanding cross-reactive immunity, aiding the development of universal influenza vaccines targeting conserved HA regions. While primarily used in research settings, its utility underscores the importance of HA-specific antibodies in both diagnostic and therapeutic contexts against evolving influenza threats.