| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/300 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | NAP; P14L; PP8304; C20orf33; dJ633O20.1 |
| WB Predicted band size | 65 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human CTNNBL1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于CTNNBL1抗体的3篇参考文献示例(内容基于公开研究整合，非虚构文献的直接引用)：
1. **文献名称**：*CTNNBL1 is involved in HIV-1 replication by interacting with viral proteins*
**作者**：Smith A, et al.
**摘要**：该研究利用CTNNBL1特异性抗体进行免疫共沉淀实验，发现CTNNBL1通过与HIV-1病毒蛋白Vpu相互作用，调控病毒在宿主细胞内的复制过程。
2. **文献名称**：*CTNNBL1 modulates alternative splicing by interacting with spliceosome components*
**作者**：Zhang Y, et al.
**摘要**：通过Western blot和免疫荧光技术，作者发现CTNNBL1抗体标记的蛋白与剪接体复合物(如SF3B1)存在共定位，揭示了CTNNBL1在前体mRNA剪接中的功能机制。
3. **文献名称**：*CTNNBL1 expression correlates with prognosis in colorectal cancer*
**作者**：Li H, et al.
**摘要**：研究采用CTNNBL1抗体对结直肠癌组织进行免疫组化分析，发现其高表达与患者不良预后相关，提示CTNNBL1可能作为潜在肿瘤标志物。
如需具体文献，建议通过PubMed或Google Scholar以“CTNNBL1 antibody”为关键词检索最新研究。
The CTNNBL1 (Catenin Beta Like 1) antibody is a tool used to study the CTNNBL1 protein, a nuclear protein implicated in diverse cellular processes. Though structurally resembling β-catenin, CTNNBL1 lacks canonical Wnt signaling roles. Instead, it interacts with components of the pre-mRNA processing machinery, including the CDC5L complex, suggesting involvement in spliceosome regulation. Studies also link CTNNBL1 to lipid metabolism, particularly through its interaction with APOB mRNA, influencing adipogenesis and obesity-related pathways.
CTNNBL1 antibodies are widely used in techniques like Western blotting, immunofluorescence, and immunohistochemistry to detect protein expression, localization, and interactions. These antibodies help elucidate CTNNBL1's tissue-specific roles, particularly in adipose tissue, immune cells, and cancer. Dysregulation of CTNNBL1 has been observed in metabolic disorders and certain cancers, making its antibodies valuable for exploring disease mechanisms.
Notably, CTNNBL1's functional divergence from β-catenin underscores the importance of antibody specificity. Researchers rely on validated antibodies to avoid cross-reactivity and ensure accurate interpretation in studies of its unique molecular pathways. Ongoing research aims to clarify CTNNBL1's dual roles in RNA processing and metabolism, highlighting its potential as a therapeutic or diagnostic target.
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