关键信息
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基因名
PSG4
- 应用
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别名
Pregnancy-specific beta-1-glycoprotein 4. PS-beta-G-4. PSBG-4. Pregnancy-specific glycoprotein 4. Pregnancy-specific beta-1-glycoprotein 9. PS-beta-G-9. PSBG-9. Pregnancy-specific glycoprotein 9
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q00888
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表达区间
1-419 aa
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氨基酸序列
MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYGGRETAYSNASLLIQNVTREDAGSYTLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLSKPYITINNLNPRENKDVLTFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPNVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPRAQYSWTINGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSITVKVSDWILP
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分子量
71.83 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
PSG4, or Pregnancy-Specific Glycoprotein 4, belongs to a family of glycoproteins primarily expressed by trophoblast cells during pregnancy. Its structure and function have garnered significant interest due to its involvement in maternal-fetal interactions, immune modulation, and potential implications in various reproductive disorders. Research has shown that PSG4 plays a role in enhancing trophoblast invasion and modulating the maternal immune response to prevent fetal rejection, thereby contributing to successful pregnancy outcomes. Given its unique expression pattern and potential functions, PSG4 has been investigated as a biomarker for complications such as preeclampsia and fetal growth restrictions. Additionally, its involvement in angiogenesis and placental development positions PSG4 as a prospective target for therapeutic interventions in pregnancy-related conditions. The study of PSG4 is increasingly relevant as its implications extend beyond reproductive health, suggesting potential roles in cancer biology and other chronic diseases, where similar glycoproteins may impact immune evasion and cellular interactions. As researchers delve deeper into the molecular mechanisms underlying PSG4's functions, its significance in both obstetrics and broader biomedical contexts continues to evolve, paving the way for innovative diagnostic and therapeutic strategies.
