Cat: PA2000-2236

Recombinant Human SYNGR1 Protein,His

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关键信息

  • 基因名

    SYNGR1

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    SYNGR1;Synaptogyrin-1

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O43759

  • 表达区间

    1-191aa

  • 氨基酸序列

    MEGGAYGAGKAGGAFDPYTLVRQPHTILRVVSWLFSIVVFGSIVNEGYLNSASEGEEFCIYNRNPNACSYGVAVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFLWFVGFCYLANQWQVSKPKDNPLNEGTDAARAAIAFSFFSIFTWSLTAALAVRRFKDLSFQEEYSTLFPASAQP

  • 分子量

    48.0 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

SYNGR1, or Synaptogyrin 1, is a protein that plays a critical role in synaptic function and neural communication. Its expression is predominantly found in the brain, where it is involved in neurotransmitter release and synaptic plasticity. Recent studies have highlighted the potential implications of SYNGR1 in neuropsychiatric disorders, including schizophrenia and autism spectrum disorders, suggesting that alterations in its function may contribute to the pathophysiology of these conditions. The recombinant versions of SYNGR1 are being explored for a variety of applications, including the investigation of its interactions with other synaptic proteins and the characterization of its role in synaptic vesicle trafficking. By producing SYNGR1 as a recombinant protein, researchers can facilitate the development of assays to study its biochemical properties, cellular localization, and functionality in vitro. This research is not only important for understanding fundamental neural mechanisms but may also pave the way for novel therapeutic strategies targeting synaptic dysfunction, offering hope for improved treatment options for individuals affected by synaptic-related neurodevelopmental disorders. As a result, SYNGR1 continues to be a focus of active research, appealing to both neuroscientists and clinicians interested in the molecular basis of brain function and mental health.

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