| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | OR9K2 |
| Uniprot No | Q8NGE7 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-335 aa |
| 活性数据 | MLGSKPRVHLYILPCASQQVSTMGDRGTSNHSEMTDFILAGFRVRPELHILLFLLFLFVY AMILLGNVGMMTIIMTDPRLNTPMYFFLGNLSFIDLFYSSVIEPKAMINFWSENKSISFA GCVAQLFLFALLIVTEGFLLAAMAYDRFIAICNPLLYSVQMSTRLCTQLVAGSYFCGCIS SVIQTSMTFTLSFCASRAVDHFYCDSRPLQRLSCSDLFIHRMISFSLSCIIILPTIIVII VSYMYIVSTVLKIHSTEGHKKAFSTCSSHLGVVSVLYGAVFFMYLTPDRFPELSKVASLC YSLVTPMLNPLIYSLRNKDVQEALKKFLEKKNIIL |
| 分子量 | 37.7 kDa |
| 蛋白标签 | His tag N-Terminus |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人OR9K2蛋白的参考文献示例，但由于该基因研究较为有限，以下内容为基于相关领域文献的模拟概括，供参考：
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1. **文献名称**：*Expression and Functional Characterization of Recombinant Human Olfactory Receptor OR9K2 in HEK293 Cells*
**作者**：Zhang L. et al.
**摘要**：研究利用HEK293细胞系统成功表达重组OR9K2蛋白，通过荧光钙离子成像技术证实其可被特定挥发性化合物激活，提示其在非嗅觉组织中的潜在信号传导功能。
2. **文献名称**：*Structural Insights into OR9K2: A Computational Approach to Olfactory Receptor Modeling*
**作者**：Kim S. & Patel R.
**摘要**：采用分子对接和同源建模预测OR9K2的三维结构，分析其与配体结合的关键位点，为开发针对该受体的调节剂提供理论依据。
3. **文献名称**：*OR9K2 Expression in Human Tissues and its Association with Metabolic Disorders*
**作者**：Wang Y. et al.
**摘要**：通过qPCR和免疫组化检测OR9K2在脂肪组织的表达，发现其与肥胖相关代谢标志物存在相关性，暗示其在脂质代谢中的潜在作用。
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**备注**：
- OR9K2属于嗅觉受体家族，相关研究较少，以上内容为模拟生成，建议通过**PubMed**或**Google Scholar**以“OR9K2”、“olfactory receptor expression”或“GPCR recombinant production”为关键词检索最新文献。
- 若研究重组蛋白技术，可参考嗅觉受体通用表达方法（如*Nature Protocols*中的GPCR表达指南）。
希望以上示例对您有帮助！
Olfactory receptor 9K2 (OR9K2) is a member of the olfactory receptor (OR) family, a large group of G protein-coupled receptors (GPCRs) responsible for detecting odorants in the nasal epithelium. ORs are characterized by seven transmembrane domains and play critical roles in recognizing and transducing odorant signals via G protein-mediated signaling cascades. OR9K2, encoded by the *OR9K2* gene, belongs to the OR9K subfamily within class II ORs, which typically detect airborne, volatile compounds. While its precise endogenous ligands remain unidentified, OR9K2 is hypothesized to participate in the perception of specific chemical cues, contributing to the combinatorial coding of olfactory information.
Recombinant OR9K2 protein is produced using heterologous expression systems (e.g., HEK293 or insect cells) to enable structural and functional studies. These systems facilitate proper folding, post-translational modifications, and membrane localization of the receptor. Recombinant OR9K2 retains its ligand-binding specificity and signaling properties, making it a valuable tool for deorphanization efforts (identifying activating ligands), studying receptor-ligand interactions, and exploring downstream signaling mechanisms. Its expression is also explored in non-olfactory tissues, suggesting potential roles in physiological processes beyond smell, though this remains underinvestigated. Research on recombinant OR9K2 contributes to understanding olfactory coding, receptor evolution, and its potential as a therapeutic target in chemosensory disorders.
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