关键信息
-
基因名
C9orf173
- 应用
-
别名
STPG3; C9orf173; Protein STPG3; Sperm-tail PG-rich repeat-containing Protein 3
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q8N7X2
-
表达区间
1-386aa
-
氨基酸序列
MMNSDQKAVKFLANFYINGGKHWTHGHLRQTQPEPTQPKASVLLLGPEPGMAWDETQPPKMKEIPVGLRLQTGTPQESLPTYTQTLRELLLEQRPLITADLEVPSPTRYQVPSPSVRESSPHPHYSIGCKHQGREGGGRRAWQTLWFQSESPFTQKADFDQEQKWPSPAHYQLLSRPAFPAFSFRGCHSASKTPEGHTHLGLPGARGLGLRVQPQSLLQASLQAPGKRCPGPNTYNILPGSRLQSPRSPAFSMSRSPAFTSWLSTSFSFGSPNPWPSRLPRGGLQLTLPFGAWRGHPGCTQTQAPRHRPLLHALEPAGHNLLGPATEWNHGLPRGFPRPPLGLGAPAWPSDPLGTPMHPSGWPTLLWAVDKAGPAWIPHLPISPLH
-
分子量
42.5 KDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
C9orf173, also known as “Chromosome 9 Open Reading Frame 173,” has emerged as a protein of interest in various biomedical research fields due to its potential involvement in cellular processes and disease mechanisms. Initially identified through genomic surveys, C9orf173 is thought to play a role in cellular stress responses and has been linked to neurodegenerative disorders, particularly amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Studies suggest that the protein might participate in regulating RNA metabolism and protein homeostasis, which are critical in maintaining cellular function. As researchers continue to explore its biological significance, recombinant C9orf173 has been produced for in vitro analysis, facilitating investigations into its functional properties and interaction networks. The ability to study C9orf173 in a controlled environment offers insights into its structure-function relationships, as well as its potential as a therapeutic target. Thus, ongoing research on the recombinant form of C9orf173 aims to uncover its specific roles in cellular pathways, contributing to a better understanding of the underlying mechanisms of neurodegenerative diseases and opening avenues for novel treatment strategies.
