关键信息
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基因名
mpt51
- 应用
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别名
mpt51；fbpC1；fbpD；mpb51；MPT51/MPB51 antigen
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种属
E.coli
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P9WQN6
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表达区间
27-299aa
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氨基酸序列
AEPTAKAAPYENLMVPSPSMGRDIPVAFLAGGPHAVYLLDAFNAGPDVSNWVTAGNAMNTLAGKGISVVAPAGGAYSMYTNWEQDGSKQWDTFLSAELPDWLAANRGLAPGGHAAVGAAQGGYGAMALAAFHPDRFGFAGSMSGFLYPSNTTTNGAIAAGMQQFGGVDTNGMWGAPQLGRWKWHDPWVHASLLAQNNTRVWVWSPTNPGASDPAAMIGQAAEAMGNSRMFYNQYRSVGGHNGHFDFPASGDNGWGSWAPQLGAMSGDIVGAIR
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分子量
44.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
The study of the MPT51 recombinant protein is rooted in the increasing need to understand and combat the infectious disease caused by Mycobacterium tuberculosis (Mtb), the bacterium responsible for tuberculosis (TB). MPT51, or M. tuberculosis protein 51, is a significant immunogenic protein that plays a crucial role in the immune response to Mtb infection. Given its ability to induce strong cellular and humoral immune responses, MPT51 has garnered interest as a potential target for vaccine development and diagnostic applications. Research has shown that MPT51 is a highly conserved protein, making it a suitable candidate for diagnostic tests to detect TB infections across different populations. Furthermore, the production of MPT51 in recombinant form allows for detailed studies on its structure, function, and potential use in immunotherapy. With rising global TB incidence and the emergence of drug-resistant strains, elucidating the properties of MPT51 could contribute significantly to advancing public health strategies aimed at controlling and eradicating TB. The ongoing research surrounding this protein underscores its importance in both basic microbiology and applied clinical contexts, potentially leading to novel interventions in the fight against one of the world’s deadliest infectious diseases.
