关键信息
-
基因名
RPL3L
- 应用
-
别名
60S ribosomal protein L3-like; Ribosomal protein L3 like; RL3L_HUMAN; RPL3L
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q92901
-
表达区间
1-407 aa
-
氨基酸序列
MSHRKFSAPR HGHLGFLPHK RSHRHRGKVK TWPRDDPSQP VHLTAFLGYK AGMTHTLREV HRPGLKISKR EEVEAVTIVE TPPLVVVGVV GYVATPRGLR SFKTIFAEHL SDECRRRFYK DWHKSKKKAF TKACKRWRDT DGKKQLQKDF AAMKKYCKVI RVIVHTQMKL LPFRQKKAHI MEIQLNGGTV AEKVAWAQAR LEKQVPVHSV FSQSEVIDVI AVTKGRGVKG VTSRWHTKKL PRKTHKGLRK VACIGAWHPA RVGCSIARAG QKGYHHRTEL NKKIFRIGRG PHMEDGKLVK NNASTSYDVT AKSITPLGGF PHYGEVNNDF VMLKGCIAGT KKRVITLRKS LLVHHSRQAV ENIELKFIDT TSKFGHGRFQ TAQEKRAFMG PQKKHLEKET PETSGDL
-
分子量
46.2 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
RPL3L, a member of the ribosomal protein family, plays a crucial role in the assembly and function of the ribosome, the cellular machinery responsible for protein synthesis. Research has shown that RPL3L is involved in various biological processes, including growth, development, and the regulation of cell cycle progression. Alterations in the expression or function of RPL3L have been linked to several diseases, particularly cancers, making it an important target for therapeutic intervention. In the context of ribosomal biogenesis, RPL3L is essential for the proper translation of mRNAs, directly influencing cellular homeostasis. Investigating RPL3L as a recombinant protein offers insights into its structural and functional properties, enabling researchers to elucidate its specific role in ribosome assembly and its impact on cellular functions under normal and pathological conditions. This line of research may facilitate the development of novel strategies for targeting ribosomal dysregulation in cancer and other diseases, potentially leading to innovative therapeutic approaches. As a result, the study of RPL3L not only advances our understanding of ribosome biology but also opens avenues for clinical applications in cancer therapy and beyond.
