| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | TEX13B |
| Uniprot No | Q9BXU2 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-312 aa |
| 活性数据 | MALRPEDPSS GFRHGNVVAF IIEKMARHTK GPEFYFENIS LSWEEVEDKL RAILEDSEVP SEVKEACTWG SLALGVRFAH RQGQLQNRRV QWLQGFAKLH RSAALVLASN LTELKEQQEM ECNEATFQLQ LTETSLAEVQ RERDMLRWKL FHAELAPPQG QGQATVFPGL ATAGGDWTEG AGEQEKEAVA AAGAAGGKGE ERYAEAGPAP AEVLQGLGGG FRQPLGAIVA GKLHLCGAEG ERSQVSTNSH VCLLWAWVHS LTGASSCPAP YLIHILIPMP FVRLLSHTQY TPFTSKGHRT GSNSDAFQLG GL |
| 分子量 | 33.9 kDa |
| 蛋白标签 | His tag N-Terminus |
| 缓冲液 | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是三篇假设性参考文献，供参考(注：实际文献需通过学术数据库核实)：
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1. **文献名称**: "Characterization of Recombinant Human TEX13B and Its Role in Germ Cell Development"
**作者**: Zhang Y. et al.
**摘要**: 本研究利用大肠杆菌系统成功表达并纯化了重组人TEX13B蛋白，验证其特异性表达于睾丸组织中。体外实验表明，TEX13B通过调控减数分裂相关基因的表达参与生殖细胞发育，为男性不育症研究提供了潜在靶点。
2. **文献名称**: "TEX13B: A Novel Testis-Specific Protein Involved in Spermatogenesis"
**作者**: Lee S., Smith R.
**摘要**: 通过构建Tex13b基因敲除小鼠模型，发现该蛋白缺失导致精子形成障碍。重组TEX13B蛋白的高效表达及抗体开发证实其在精子发生过程中的动态定位，提示其可能在染色质重塑中发挥功能。
3. **文献名称**: "Structural and Functional Analysis of TEX13B Protein Using Recombinant Expression System"
**作者**: Kumar A. et al.
**摘要**: 采用杆状病毒-昆虫细胞系统重组表达TEX13B，通过冷冻电镜解析其三维结构，揭示其独特的RNA结合结构域。功能实验表明，该蛋白可能通过与生殖细胞特异性mRNA互作调控翻译过程。
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**提示**：以上为示例性内容，TEX13B相关研究文献在真实数据库中可能有限。建议通过PubMed、Web of Science等平台以关键词“TEX13B”、“recombinant protein”、“spermatogenesis”等进一步检索。
**Background of Recombinant Human TEX13B Protein**
TEX13B (Testis Expressed 13B) is a protein-coding gene predominantly expressed in the testis, suggesting a potential role in spermatogenesis or germ cell development. It belongs to the TEX gene family, which includes several members implicated in reproductive biology, particularly in processes like meiosis, chromatin remodeling, or post-transcriptional regulation. TEX13B shares homology with TEX13A, but its distinct expression pattern and functional divergence remain under investigation.
As a recombinant protein, TEX13B is produced *in vitro* using expression systems (e.g., *E. coli* or mammalian cells) to enable functional studies. Its recombinant form allows researchers to explore its interactions, post-translational modifications, and potential involvement in cellular pathways. While its exact biological mechanism is unclear, preliminary studies link TEX13B to mRNA metabolism or translational regulation in germ cells, possibly through RNA-binding domains predicted in its structure.
Interest in TEX13B also extends to clinical research, as dysregulation of testis-specific genes is often associated with infertility or germ cell tumors. Recombinant TEX13B facilitates antibody development for diagnostic tools or biomarker discovery. However, comprehensive studies are needed to clarify its physiological roles, tissue-specific regulation, and relevance in diseases. Current efforts focus on unraveling its molecular interactions and validating its functional significance in models of reproduction and cancer.
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